Latest & greatest articles for analgesia

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This page lists the very latest high quality evidence on analgesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Analgesia

Analgesic drugs are used to provide analgesia, the inability to feel pain. There are numerous groups of analgesics including simple analgesics, non-steroidal anti-inflammatory drugs (NSAIDs) and opioids. Analgesics types are prescribed differently depending on the severity of pain relief needed.

The most common type of analgesic generally known and used is non-steroidal anti-inflammatory drugs such as paracetamol, aspirin and ibuprofen. Opioid drugs include morphine, codeine, oxycodone, dihydromorphine and pethidine.

Research shows that analgesic drugs have an effect on the peripheral and central nervous system, relieving pain without the loss of consciousness. Opioids are highly effect pain relievers however case studies prove they can be highly addictive. Therefore use should be guided by the World Health Organization (WHO) pain ladder which specifies mild analgesics as its first step.

Clinical trials and studies carried out across all groups of analgesia have proven the drugs are highly effective painkillers, opioids in particular. However, years of research and clinical trials conclude that some groups have significant side effects such as addiction or cardiovascular side effects. Research evidence is broad including clinical guidelines, systematic reviews, randomised controlled trials, case studies etc. These can easily be found via a search of the Trip Database.

Top results for analgesia

1. Sensation of Pain Using Buffered Lidocaine for Infiltration Before Vulvar Biopsy: A Randomized Controlled Trial

Sensation of Pain Using Buffered Lidocaine for Infiltration Before Vulvar Biopsy: A Randomized Controlled Trial Sensation of Pain Using Buffered Lidocaine for Infiltration Before Vulvar Biopsy: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library of Medicine (...) Obstet Gynecol Actions . 2020 Mar;135(3):609-614. doi: 10.1097/AOG.0000000000003710. Sensation of Pain Using Buffered Lidocaine for Infiltration Before Vulvar Biopsy: A Randomized Controlled Trial , , , , , , Affiliations Expand Affiliation 1 Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan; and the Department of Obstetrics and Gynecology, the Program in Women's Oncology, Division of Research, Department of Obstetrics and Gynecology, and the Program in Women's

2020 EvidenceUpdates

2. Consensus Practice Guidelines on Interventions for Lumbar Facet Joint Pain from a Multispecialty, International Working Group Full Text available with Trip Pro

Consensus Practice Guidelines on Interventions for Lumbar Facet Joint Pain from a Multispecialty, International Working Group Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group | Regional Anesthesia & Pain Medicine Log in via your Society Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search (...) for this keyword Main menu Log in via your Society Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group Article Text Special article Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group Steven P Cohen

2020 American Society of Regional Anesthesia and Pain Medicine

3. Reduction of Postoperative Hip Arthroscopy Pain With an Ultrasound-Guided Fascia Iliaca Block: A Prospective Randomized Controlled Trial

Reduction of Postoperative Hip Arthroscopy Pain With an Ultrasound-Guided Fascia Iliaca Block: A Prospective Randomized Controlled Trial Reduction of Postoperative Hip Arthroscopy Pain With an Ultrasound-Guided Fascia Iliaca Block: A Prospective Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National (...) Actions Cite Share Permalink Copy Page navigation Am J Sports Med Actions . 2020 Mar;48(3):682-688. doi: 10.1177/0363546519898205. Epub 2020 Jan 30. Reduction of Postoperative Hip Arthroscopy Pain With an Ultrasound-Guided Fascia Iliaca Block: A Prospective Randomized Controlled Trial , , , , , , Affiliations Expand Affiliations 1 Steadman Hawkins Clinic of the Carolinas, Prisma Health-Upstate, Greenville, South Carolina, USA. 2 Prisma Health-Upstate, Greenville, South Carolina, USA. 3 Mayo Clinic

2020 EvidenceUpdates

4. Efficacy and safety of multiple doses of tapentadol oral solution in the treatment of moderate to severe acute pain in children aged 2 to <18 years - a randomized, double-blind, placebo-controlled trial Full Text available with Trip Pro

-controlled analgesia. Figure 2 5 Patient flow chart. Notes: “Recovery... Figure 2 13 Patient flow chart. Notes: “Recovery” denotes that opioid analgesic medication is no longer... Figure 2 Patient flow chart. Notes: “Recovery” denotes that opioid analgesic medication is no longer required. “Physician decision” denotes the switch to exclusively oral opioid analgesic medication indicated according to local standard of care. a All patients treated with study medication were included in the full analysis set (...) Efficacy and safety of multiple doses of tapentadol oral solution in the treatment of moderate to severe acute pain in children aged 2 to <18 years - a randomized, double-blind, placebo-controlled trial Efficacy and Safety of Multiple Doses of Tapentadol Oral Solution in the Treatment of Moderate to Severe Acute Pain in Children Aged 2 to - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History

2020 EvidenceUpdates

5. The effect of expressed breast milk, swaddling and facilitated tucking methods in reducing the pain caused by orogastric tube insertion in preterm infants: A randomized controlled trial

in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Int J Nurs Stud Actions . 2020 Apr;104:103532. doi: 10.1016/j.ijnurstu.2020.103532. Epub 2020 Jan 24. The Effect of Expressed Breast Milk, Swaddling and Facilitated Tucking Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants: A Randomized Controlled Trial , Affiliations Expand Affiliations 1 Child Health Nursing Department (...) the facilitated tucking group had 6.301, the facilitated tucking+expressed breast milk group had 3.107, the control group had 13.015, and the swaddling group had 7.892 times more pain. Conclusion: The swaddling+expressed breast milk method is clinically better pain relief nonpharmalogical option and is the recommended method to nurses for the orogastric tube insertion procedures, preterm infants. Keywords: Newborn nurse; Orogastric tube; Pain; Premature; Preterm. Copyright © 2020. Published by Elsevier Ltd

2020 EvidenceUpdates

6. A Double-Blind, Randomized Controlled Trial of Pre-incision Wound Infiltration Using Diclofenac Versus Bupivacaine for Post-operative Pain Relief in Open Thyroid and Parathyroid Surgery

in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation World J Surg Actions . 2020 Mar 19. doi: 10.1007/s00268-020-05458-6. Online ahead of print. A Double-Blind, Randomized Controlled Trial of Pre-incision Wound Infiltration Using Diclofenac Versus Bupivacaine for Post-operative Pain Relief in Open Thyroid and Parathyroid Surgery , , , Affiliations Expand Affiliations 1 Department of Surgery, University (...) A Double-Blind, Randomized Controlled Trial of Pre-incision Wound Infiltration Using Diclofenac Versus Bupivacaine for Post-operative Pain Relief in Open Thyroid and Parathyroid Surgery A Double-Blind, Randomized Controlled Trial of Pre-incision Wound Infiltration Using Diclofenac Versus Bupivacaine for Post-operative Pain Relief in Open Thyroid and Parathyroid Surgery - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features

2020 EvidenceUpdates

7. A Comparison of Intrathecal and Intravenous Morphine for Analgesia After Hepatectomy: A Randomized Controlled Trial Full Text available with Trip Pro

aimed to evaluate the effects of the addition of preoperative intrathecal morphine to multimodal intravenous analgesia in patients undergoing liver resection. Methods: In this single-blind randomized controlled trial, patients undergoing liver resection were randomly assigned to the patient-controlled analgesia with (ITM-IV) or without (IV) preoperative intrathecal morphine groups. All patients received acetaminophen and dexketoprofen. The primary outcome was pain severity at rest over three (...) A Comparison of Intrathecal and Intravenous Morphine for Analgesia After Hepatectomy: A Randomized Controlled Trial A Comparison of Intrathecal and Intravenous Morphine for Analgesia After Hepatectomy: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library

2020 EvidenceUpdates

8. Erector spinae plane versus paravertebral nerve blocks for postoperative analgesia after breast surgery: a randomized clinical trial

Share Permalink Copy Page navigation Reg Anesth Pain Med Actions . 2020 Apr;45(4):260-266. doi: 10.1136/rapm-2019-101013. Epub 2020 Jan 21. Erector Spinae Plane Versus Paravertebral Nerve Blocks for Postoperative Analgesia After Breast Surgery: A Randomized Clinical Trial , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Anesthesiology, University of California San Diego, San Diego, California, USA mwswisher@ucsd.edu. 2 Surgery, University of California San Diego, San Diego, California (...) , USA. 3 Anesthesiology, University of California San Diego, San Diego, California, USA. 4 Biomedical Informatics, University of California San Diego, San Diego, California, United States. 5 Neurology, University of Southern California, Los Angeles, California, USA. PMID: 31969443 DOI: Item in Clipboard Erector Spinae Plane Versus Paravertebral Nerve Blocks for Postoperative Analgesia After Breast Surgery: A Randomized Clinical Trial Matthew W Swisher et al. Reg Anesth Pain Med . 2020 Apr . Show

2020 EvidenceUpdates

9. The effectiveness of an aerobic exercise training on patients with neck pain during a short- and long-term follow-up: a prospective double-blind randomized controlled trial

Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Clin Rehabil Actions . 2020 May;34(5):617-629. doi: 10.1177/0269215520912000. Epub 2020 Mar 17. The Effectiveness of an Aerobic Exercise Training on Patients With Neck Pain During a Short- And Long-Term Follow-Up: A Prospective Double-Blind Randomized Controlled Trial , , , , Affiliations Expand Affiliations 1 Department of Physical Therapy, Faculty of Social Welfare & Health (...) , Netanya, Israel. PMID: 32183555 DOI: Item in Clipboard Full-text links Cite Abstract Objective: To examine the effect of adding aerobic exercise (AE) to neck-specific exercise treatment for patients with neck pain (NP) to reduce pain and disability. Design: A prospective multicentre randomized controlled trial. Setting: Physiotherapy outpatient clinics. Subjects: Patients with nonspecific NP. Intervention: Patients with NP were randomly assigned to six weeks of neck-specific exercise with and without

2020 EvidenceUpdates

10. Does adding case management to standard rehabilitation affect functional ability, pain, or the rate of return to work after lumbar spinal fusion? A randomized controlled trial with two-year follow-up

Does adding case management to standard rehabilitation affect functional ability, pain, or the rate of return to work after lumbar spinal fusion? A randomized controlled trial with two-year follow-up Does Adding Case Management to Standard Rehabilitation Affect Functional Ability, Pain, or the Rate of Return to Work After Lumbar Spinal Fusion? A Randomized Controlled Trial With Two-Year Follow-Up - PubMed This site needs JavaScript to work properly. Please enable it to take advantage (...) ? Report format: Send at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Clin Rehabil Actions . 2020 Mar;34(3):357-368. doi: 10.1177/0269215519897106. Epub 2020 Jan 22. Does Adding Case Management to Standard Rehabilitation Affect Functional Ability, Pain, or the Rate of Return to Work After Lumbar Spinal Fusion? A Randomized Controlled Trial

2020 EvidenceUpdates

11. Consensus Practice Guidelines on Interventions for Lumbar Facet Joint Pain

facetogenic pain; ? Lack of information on important outcome measures. More information may allow estimation of effects on treatment outcomes. grading of evidence guidelines, with the level of certainty rated as high, medium or low (tables 1–3). 29 This system, which has been modified for use in interventional pain management guide- lines drafted by the American Society of Regional Anesthesia & Pain Medicine, American Academy of Pain Medicine, American Society of Anesthesiologists, American Society (...) Pain Med: first published as 10.1136/rapm-2019-101243 on 3 April 2020. Downloaded from 4 Cohen SP , et al. Reg Anesth Pain Med 2020;0:1–44. doi:10.1136/rapm-2019-101243 Special article Table 4 Studies evaluating physical examination findings and facet block results Study design/criteria for positive block Interventions findings Fairbank et al 37 Prospective n=25 Subjective pain relief IA (double blocks, one injection at symptomatic level, another at a random level) Responders: pain in the back

2020 American Academy of Pain Medicine

12. Pain Management Best Practices from Multispecialty Organizations during the COVID-19 Pandemic and Public Health Crises

and Rehabilitation, Walter Reed National Military Medical Center, Uniformed Services University of the Health Sciences , Bethesda, MD Corresponding Author: Steven P. Cohen, M.D. Pain Medicine, Dept. of Anesthesiology and Critical Care Medicine, 550 N. Broadway, Suite 301, Baltimore, MD 21205. Tel: 410-955-7246; E-mail: Search for other works by this author on: , Zafeer B Baber, MD Division of Anesthesiology and Interventional Pain Management, Lahey Hospital & Medical Center , Beth Israel Lahey Health, Burlington (...) , conservation of resources, and access to pain management services. Specific issues discussed include general and interventional-specific risk mitigation, patient flow issues and staffing plans, telemedicine options, triaging recommendations, strategies to reduce psychological sequelae in health care providers, and resource utilization. Conclusions The COVID-19 public health crisis has strained health care systems, creating a conundrum for patients, pain medicine practitioners, hospital leaders

2020 American Academy of Pain Medicine

13. Comparison of Early-Stage and Late-Stage Periarticular Injection for Pain Relief After Total Hip Arthroplasty: A Double-Blind Randomized Controlled Trial

in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation J Arthroplasty Actions . 2019 Dec 17;S0883-5403(19)31169-6. doi: 10.1016/j.arth.2019.12.020. Online ahead of print. Comparison of Early-Stage and Late-Stage Periarticular Injection for Pain Relief After Total Hip Arthroplasty: A Double-Blind Randomized Controlled Trial , , , , , Affiliations Expand Affiliations 1 Department of Orthopaedic Surgery, Hokusuikai (...) controlled trial. Keywords: analgesia; hip; local infiltration analgesia; pain management; periarticular injection; total hip arthroplasty. Copyright © 2019 Elsevier Inc. All rights reserved. Similar articles Tsukada S, Kurosaka K, Maeda T, Iida A, Nishino M, Hirasawa N. Tsukada S, et al. Knee Surg Sports Traumatol Arthrosc. 2019 Apr;27(4):1124-1131. doi: 10.1007/s00167-018-5140-y. Epub 2018 Sep 20. Knee Surg Sports Traumatol Arthrosc. 2019. PMID: 30238239 Free PMC article. Clinical Trial. Tsukada S

2020 EvidenceUpdates

14. Comparison of quadratus lumborum block and caudal block for postoperative analgesia in pediatric patients undergoing inguinal hernia repair and orchiopexy surgeries: a randomized controlled trial

: Send at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Reg Anesth Pain Med Actions . 2020 Mar;45(3):187-191. doi: 10.1136/rapm-2019-101027. Epub 2020 Jan 5. Comparison of Quadratus Lumborum Block and Caudal Block for Postoperative Analgesia in Pediatric Patients Undergoing Inguinal Hernia Repair and Orchiopexy Surgeries: A Randomized (...) =0.001 and p<0.001, respectively). Parent satisfaction scores were higher in the QLB group (p=0.014). Conclusion: According to the results of this study, QLB can provide much more effective analgesia than caudal block without adjuvants in multimodal analgesia management of children undergoing inguinal hernia repair and orchiopexy surgeries. Trial registration number: . Keywords: Pediatric pain; postoperative pain; truncal blocks. © American Society of Regional Anesthesia & Pain Medicine 2020

2020 EvidenceUpdates

15. Effects of virtual reality on pain, fear and anxiety during blood draw in children aged 5-12 years old: A randomised controlled study

citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation J Clin Nurs Actions . 2020 Apr;29(7-8):1151-1161. doi: 10.1111/jocn.15173. Epub 2020 Jan 22. Effects of Virtual Reality on Pain, Fear and Anxiety During Blood Draw in Children Aged 5-12 Years Old: A Randomised Controlled Study , , , Affiliations Expand Affiliation 1 Pediatric Nursing Department, Dokuz Eylul University Faculty of Nursing, Izmir, Turkey. PMID: 31889358 DOI: Item in Clipboard Effects (...) Clinics, Dental Prospects, 6, 117-124. https://doi.org/10.5681/joddd.2012.025 Arane, K., Behboudi, A., & Goldman, R. D. (2017). Virtual reality for pain and anxiety management in children. Canadian Family Physician, 63, 932-934. Atzori, B., Lauro Grotto, R., Giugni, A., Calabrò, M., Alhalabi, W., & Hoffman, H. G. (2018). Virtual reality analgesia for pediatric dental patients. Frontiers in Psychology, 9, 2265. https://doi.org/10.3389/fpsyg.2018.02265 Aydin, D., & Sahiner, N. C. (2017). Effects

2020 EvidenceUpdates

16. Effectiveness of physical therapy treatment in addition to usual podiatry management of plantar heel pain: a randomized clinical trial Full Text available with Trip Pro

Effectiveness of physical therapy treatment in addition to usual podiatry management of plantar heel pain: a randomized clinical trial Effectiveness of Physical Therapy Treatment in Addition to Usual Podiatry Management of Plantar Heel Pain: A Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced (...) characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation BMC Musculoskelet Disord Actions , 20 (1), 630 2019 Dec 28 Effectiveness of Physical Therapy Treatment in Addition to Usual Podiatry Management of Plantar Heel Pain: A Randomized Clinical Trial , , , Affiliations Expand Affiliations 1 Doctor of Physical Therapy Program

2020 EvidenceUpdates

17. Effect of bilateral scalp nerve blocks on postoperative pain and discharge times in patients undergoing supratentorial craniotomy and general anesthesia: a randomized-controlled trial (Abstract)

Effect of bilateral scalp nerve blocks on postoperative pain and discharge times in patients undergoing supratentorial craniotomy and general anesthesia: a randomized-controlled trial Post-craniotomy pain is a common clinical issue and its optimal management remains incompletely studied. Utilization of a regional scalp block has the potential advantage of reducing perioperative pain and opioid consumption, thereby facilitating optimal postoperative neurologic assessment. The purpose (...) of this study was to assess the efficacy of regional scalp block on post-craniotomy pain and opioid consumption.We performed a prospective randomized-controlled trial in adults scheduled to undergo elective supratentorial craniotomy under general anesthesia to assess the efficacy of postoperative bilateral scalp block with 0.5% bupivacaine with 1:200,000 epinephrine compared with placebo on postoperative pain and opioid consumption. The primary outcome was the visual analogue scale (VAS) for pain at 24 hr

2020 EvidenceUpdates

18. Randomized clinical trial of continuous transversus abdominis plane block, epidural or patient-controlled analgesia for patients undergoing laparoscopic colorectal cancer surgery Full Text available with Trip Pro

Randomized clinical trial of continuous transversus abdominis plane block, epidural or patient-controlled analgesia for patients undergoing laparoscopic colorectal cancer surgery The optimal analgesia regimen after laparoscopic colorectal cancer surgery is unclear. The aim of the study was to characterize the beneficial effects of continuous transversus abdominis plane (TAP) blocks initiated before operation on outcomes following laparoscopic colorectal cancer surgery.Patients undergoing (...) surgery for colorectal cancer were divided randomly into three groups: combined general-TAP anaesthesia (TAP group), combined general-thoracic epidural anaesthesia (TEA group) and standard general anaesthesia (GA group). The primary endpoint was duration of hospital stay. Secondary endpoints included gastrointestinal motility, pain scores and plasma levels of cytokines.In total, 180 patients were randomized and 165 completed the trial. The intention-to-treat analysis showed that duration of hospital

2020 EvidenceUpdates

19. Effect of lidocaine cream analgesia for chest drain tube removal after video-assisted thoracoscopic surgery for lung cancer: a randomized clinical trial (Abstract)

Effect of lidocaine cream analgesia for chest drain tube removal after video-assisted thoracoscopic surgery for lung cancer: a randomized clinical trial Pain management makes an important contribution to good respiratory care and early recovery after thoracic surgery. Although the development of video-assisted thoracoscopic surgery (VATS) has led to improved patient outcomes, chest tube removal could be distressful experience for many patients. The aim of this trial was to test whether (...) significantly lower in Group L than Group P (p=0.0002 vs p<0.0001).Analgesia using lidocaine cream is a very simple way to reduce the pain of chest tube removal after VATS.UMIN000013824.© American Society of Regional Anesthesia & Pain Medicine 2019. No commercial re-use. See rights and permissions. Published by BMJ.

2020 EvidenceUpdates

20. Comparison of the Efficacy Between Transurethral Coagulation and Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients: A Prospective Randomized Controlled Trial (Abstract)

Comparison of the Efficacy Between Transurethral Coagulation and Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients: A Prospective Randomized Controlled Trial Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition characterized by chronic pelvic pain related to the bladder with no effective treatment options.To evaluate the efficacy and safety of transurethral resection (TUR) and transurethral coagulation (TUC) as treatments (...) for Hunner lesion (HL) in IC/BPS.A single-center, prospective, randomized controlled trial involving 126 patients with HL in IC/BPS.TUR or TUC.Primary outcome was recurrence-free time after surgery. Secondary outcomes included change of the number of frequency, nocturia, urgency episodes in voiding diaries, O'Leary-Sant Interstitial Cystitis Symptom Index (ICSI) and Interstitial Cystitis Problem Index (ICPI), pelvic pain and urgency/frequency (PUF) symptom scale, and visual analog scale (VAS) for pain

2020 EvidenceUpdates