Latest & greatest articles for heart failure

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Top results for heart failure

1. Position Statement on COVID-19 and Acute Heart Failure: screening the critically ill

of heart failure, whilst nearly 60% had elevated biochemical markers consistent with acute cardiac injury [4]. In two separate cohort studies from Wuhan [3,5], the proportion of COVID-19 patients with evidence of cardiac injury [as defined by elevated levels of high sensitivity troponin (hsTn) with or without other biochemical markers] ranged from 20 to 28%. In both studies, patients with elevated hsTn were older and more likely to have a range of cardiovascular comorbidities including hypertension (...) , diabetes, coronary artery disease and prior heart failure. In both studies, an elevated hsTn was associated with a marked increase in mortality: 50-60% in those with an elevated hsTn compared with a mortality rate of 5-10% for those who had a normal hsTn during hospitalisation. In addition, COVID-19 patients with elevated hsTn during admission experienced higher rates of acute respiratory distress syndrome (ARDS) necessitating higher rates of non-invasive and invasive ventilation, acute renal failure

2020 Cardiac Society of Australia and New Zealand

2. Management of the Hospitalized COVID-19 Patient With Acute Cardiomyopathy or Heart Failure

L. How to balance acute myocardial infarction and COVID-19: the protocols from Sichuan Provincial People's Hospital. Intensive Care Med 2020;March 11:[Epub ahead of print]. Li H, Zhou Y, Zhang M, Wang H, Zhao Q, Liu J. Updated approaches against SARS-CoV-2. Antimicrob Agents Chemother 2020;March 23:[Epub ahead of print]. Share via: Clinical Topics: Keywords: Acute Coronary Syndrome, Anticoagulants, Arrhythmias, Cardiac, Cardiac Surgical Procedures, Metabolic Syndrome X, Angina, Stable, Heart (...) Management of the Hospitalized COVID-19 Patient With Acute Cardiomyopathy or Heart Failure Feature | Management of the Hospitalized COVID-19 Patient With Acute Cardiomyopathy or Heart Failure - American College of Cardiology ') Search All Types Search or Menu This article was authored by Joel D. Schilling, MD, PhD , Washington University School of Medicine, St. Louis, MO; Ashwin K. Ravichandran, MD, FACC , St. Vincent's Medical Group, Indianapolis, IN; and Stacy A. Mandras, MD, FACC , Oschner

2020 American College of Cardiology

3. Association of Intensive Lifestyle Intervention, Fitness, and Body Mass Index With Risk of Heart Failure in Overweight or Obese Adults With Type 2 Diabetes Mellitus: An Analysis From the Look AHEAD Trial

Association of Intensive Lifestyle Intervention, Fitness, and Body Mass Index With Risk of Heart Failure in Overweight or Obese Adults With Type 2 Diabetes Mellitus: An Analysis From the Look AHEAD Trial Association of Intensive Lifestyle Intervention, Fitness, and Body Mass Index With Risk of Heart Failure in Overweight or Obese Adults With Type 2 Diabetes Mellitus: An Analysis From the Look AHEAD Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage (...) any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Circulation Actions . 2020 Apr 21;141(16):1295-1306. doi: 10.1161/CIRCULATIONAHA.119.044865. Epub 2020 Mar 5. Association of Intensive Lifestyle Intervention, Fitness, and Body Mass Index With Risk of Heart Failure in Overweight or Obese Adults With Type 2 Diabetes Mellitus: An Analysis From the Look AHEAD Trial

2020 EvidenceUpdates

4. Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement on the Evaluation and Management of Patients With Cardiac Amyloidosis Full Text available with Trip Pro

Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement on the Evaluation and Management of Patients With Cardiac Amyloidosis Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement on the Evaluation and Management of Patients With Cardiac Amyloidosis - Canadian Journal of Cardiology Go search , P322-334, March 01, 2020 Powered By Mendeley Share on Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position (...) Columbia, Canada Sean A. Virani Affiliations University of British Columbia, Vancouver, British Columbia, Canada Shelley Zieroth Affiliations University of Manitoba, Winnipeg, Manitoba, Canada DOI: Abstract Cardiac amyloidosis is an under-recognized and potentially fatal cause of heart failure and other cardiovascular manifestations. It is caused by deposition of misfolded precursor proteins as fibrillary amyloid deposits in cardiac tissues. The two primary subtypes of systemic amyloidosis causing

2020 Canadian Cardiovascular Society

5. Is it COVID-19 or Is it Heart Failure? Management of Ambulatory Heart Failure Patients

Is it COVID-19 or Is it Heart Failure? Management of Ambulatory Heart Failure Patients GUIDANCE FROM THE CCS COVID-19 RAPID RESPONSE TEAM Is it COVID-19 or Is it Heart Failure? Management of Ambulatory Heart Failure Patients Introduction To preserve healthcare resources and prevent vulnerable patients from being unnecessarily exposed to healthcare facilities and the Emergency Department (ED), healthcare practitioners are screening patients via virtual assessment (phone, telehealth or regionally (...) available platforms), in order to determine the appropriate diagnostic and treatment approach. The following is simple, practical guidance on patient evaluation and use of laboratory testing. Symptom evaluation The following tool is designed to guide your clinical reasoning to differentiate the likely etiology of symptoms for a patient with known heart failure (HF). It has not been validated, and the final determination must be made using clinical judgement. In cases of uncertainty, patients should

2020 Canadian Cardiovascular Society

6. OUTSMART HF: A Randomized Controlled Trial of Routine Versus Selective Cardiac Magnetic Resonance for Patients With Nonischemic Heart Failure (IMAGE-HF 1B)

OUTSMART HF: A Randomized Controlled Trial of Routine Versus Selective Cardiac Magnetic Resonance for Patients With Nonischemic Heart Failure (IMAGE-HF 1B) OUTSMART HF: A Randomized Controlled Trial of Routine Versus Selective Cardiac Magnetic Resonance for Patients With Nonischemic Heart Failure (IMAGE-HF 1B) - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard (...) in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Circulation Actions . 2020 Mar 10;141(10):818-827. doi: 10.1161/CIRCULATIONAHA.119.043964. Epub 2020 Jan 8. OUTSMART HF: A Randomized Controlled Trial of Routine Versus Selective Cardiac Magnetic Resonance for Patients With Nonischemic Heart Failure (IMAGE-HF 1B) , , , , , , , , , , , , , , , , , , , Collaborators, Affiliations Expand Collaborators IMAGE-HF

2020 EvidenceUpdates

7. 2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists

of selected AHFTC specialists on the basis of background, specialized knowledge, skills, experience, and practice focus (right column). This distinction is particularly relevant to the patient care competencies and recognizes diversity in the focus of practice of AHFTC specialists. Some physicians may specialize in a particular aspect of AHFTC, such as mechanical circulatory support or cardiac transplantation, while others may adopt a practice focused on patients with chronic heart failure with a lesser (...) , there is a growing subspecialization career focus within AHFTC. Specifically, some practitioners limit the scope of their clinical activity to treating patients with advanced heart failure, including those who undergo implantation of a durable ventricular assist device or cardiac transplantation, while others focus on disease management of patients with less advanced heart failure. Thus, although maintenance of some AHFTC competencies is an expectation for all clinical AHFTC specialists, the maintenance

2020 International Society for Heart and Lung Transplantation

8. CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgitation, SGLT2 Inhibitors, ARNI in HFpEF, and Tafamidis in Amyloidosis Full Text available with Trip Pro

CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgitation, SGLT2 Inhibitors, ARNI in HFpEF, and Tafamidis in Amyloidosis CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgitation, SGLT2 Inhibitors, ARNI in HFpEF, and Tafamidis in Amyloidosis - Canadian Journal of Cardiology Go search , P159-169, February 01, 2020 Powered By Mendeley CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgitation (...) . DOI: Abstract In this update, we focus on selected topics of high clinical relevance for health care providers who treat patients with heart failure (HF), on the basis of clinical trials published after 2017. Our objective was to review the evidence, and provide recommendations and practical tips regarding the management of candidates for the following HF therapies: (1) transcatheter mitral valve repair in HF with reduced ejection fraction; (2) a novel treatment for transthyretin amyloidosis

2020 Canadian Cardiovascular Society

9. CA125-Guided Diuretic Treatment Versus Usual Care in Patients With Acute Heart Failure and Renal Dysfunction (Abstract)

CA125-Guided Diuretic Treatment Versus Usual Care in Patients With Acute Heart Failure and Renal Dysfunction The optimal diuretic treatment strategy for patients with acute heart failure and renal dysfunction remains unclear. Plasma carbohydrate antigen 125 (CA125) is a surrogate of fluid overload and a potentially valuable tool for guiding decongestion therapy. The aim of this study was to determine if a CA125-guided diuretic strategy is superior to usual care in terms of short-term renal (...) function in patients with acute heart failure and renal dysfunction at presentation.This multicenter, open-label study randomized 160 patients with acute heart failure and renal dysfunction into 2 groups (1:1). Loop diuretics doses were established according to CA125 levels in the CA125-guided group (n = 79) and in clinical evaluation in the usual-care group (n = 81). Changes in estimated glomerular filtration rate (eGFR) at 72 and 24 hours were the co-primary endpoints, respectively.The mean age

2020 EvidenceUpdates

10. Heart Failure - Systolic Dysfunction

or wall thickness. Gated SPECT may have better inter-observer reliability than echocardiography in assessing ejection fraction. However, the cost and radiation exposure support echocardiography as an appropriate initial evaluation. Functional testing. Exercise stress testing may have a role in the evaluation of some patients with heart failure. Exercise stress testing is useful in evaluating active and significant concomitant coronary artery disease and in assessing functional capacity (...) (dobutamine or dopamine) or phosphodiesterase inhibitors (milrinone) may have a role in the treatment of patients hospitalized for acutely decompensated heart failure who do not respond adequately or in a timely manner to diuretic therapy. Inotropic agents may increase cardiac output and decrease systemic and pulmonary vascular resistance. Although these therapies may improve symptoms and decrease hospitalizations, they are associated with increased mortality. Intermittent bolus or continuous home

2020 University of Michigan Health System

11. Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart Failure (Abstract)

Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart Failure While disease-modifying therapies exist for heart failure (HF) with reduced left ventricular ejection fraction (LVEF), few options are available for patients in the higher range of LVEF (>40%). Sacubitril/valsartan has been compared with a renin-angiotensin-aldosterone-system inhibitor alone in 2 similarly designed clinical trials of patients with reduced and preserved LVEF, permitting examination of its effects (...) across the full spectrum of LVEF.We combined data from PARADIGM-HF (LVEF eligibility≤40%; n=8399) and PARAGON-HF (LVEF eligibility≥45%; n=4796) in a prespecified pooled analysis. We divided randomized patients into LVEF categories: ≤22.5% (n=1269), >22.5% to 32.5% (n=3987), >32.5% to 42.5% (n=3143), > 42.5% to 52.5% (n=1427), > 52.5% to 62.5% (n=2166), and >62.5% (n=1202). We assessed time to first cardiovascular death and HF hospitalization, its components, and total heart failure hospitlizations

2020 EvidenceUpdates

12. Effects of Sacubitril-Valsartan, versus Valsartan, in Women Compared to Men with Heart Failure and Preserved Ejection Fraction: Insights from PARAGON-HF (Abstract)

older and had more obesity, less coronary disease, and lower estimated glomerular filtration rate and NT-proBNP (N-terminal pro-B-type natriuretic peptide) levels than men. For the primary outcome, the rate ratio for sacubitril-valsartan versus valsartan was 0.73 (95% CI, 0.59-0.90) in women and 1.03 (95% CI, 0.84-1.25) in men (P interaction = 0.017). The benefit from sacubitril-valsartan was attributable to reduction in heart failure hospitalization. The improvement in New York Heart Association (...) Effects of Sacubitril-Valsartan, versus Valsartan, in Women Compared to Men with Heart Failure and Preserved Ejection Fraction: Insights from PARAGON-HF Unlike heart failure with reduced ejection fraction, there is no approved treatment for heart failure with preserved ejection fraction, the predominant phenotype in women. Therefore, there is a greater heart failure therapeutic deficit in women compared with men.In a prespecified subgroup analysis, we examined outcomes according to sex

2020 EvidenceUpdates

13. Effects of Dapagliflozin on Symptoms, Function, and Quality of Life in Patients With Heart Failure and Reduced Ejection Fraction: Results From the DAPA-HF Trial Full Text available with Trip Pro

Effects of Dapagliflozin on Symptoms, Function, and Quality of Life in Patients With Heart Failure and Reduced Ejection Fraction: Results From the DAPA-HF Trial Effects of Dapagliflozin on Symptoms, Function, and Quality of Life in Patients With Heart Failure and Reduced Ejection Fraction: Results From the DAPA-HF Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go (...) your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Circulation Actions , 141 (2), 90-99 2020 Jan 14 Effects of Dapagliflozin on Symptoms, Function, and Quality of Life in Patients With Heart Failure and Reduced Ejection Fraction: Results From the DAPA-HF Trial

2020 EvidenceUpdates

14. Heart failure with preserved ejection fraction: are angiotensin receptor-neprilysin inhibitors the answer?

been promising results that sacubitril/valsartan may also benefit patients with HFpEF. In the 2012 phase 2 PARAMOUNT trial comparing sacubitril/valsartan to valsartan in patients with an LVEF > 45% and a documented history of heart failure, ARNI therapy was shown to have beneficial effects on surrogate endpoints: biomarkers indicative of heart failure progression as well as echocardiographic evidence of cardiac remodeling. At 12 weeks of follow-up, ARNI therapy was associated with a significantly (...) populations who may demonstrate true benefit from the drug. Commentary by Dr. Adam Skolnick The main challenge in studying heart failure with preserved ejection fraction (HFpEF) is that there are at least four associated phenotypes: aging, obesity, pulmonary hypertension, and coronary artery disease. 16 Combining all phenotypes into one study runs the risk of missing a subtype of HFpEF for which there is benefit or harm. Future studies should attempt to study each phenotype of HFpEF separately in order

2020 Clinical Correlations

15. Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure Full Text available with Trip Pro

Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health U.S. National Library of Medicine (...) Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Am Coll Cardiol Actions , 74 (23), 2893-2904 2019 Dec 10 Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure , , , , , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom; Centre of Cardiovascular Research and Education

2020 EvidenceUpdates

16. Cost-Effectiveness of Transcatheter Mitral Valve Repair Versus Medical Therapy in Patients With Heart Failure and Secondary Mitral Regurgitation: Results From the COAPT Trial

Cost-Effectiveness of Transcatheter Mitral Valve Repair Versus Medical Therapy in Patients With Heart Failure and Secondary Mitral Regurgitation: Results From the COAPT Trial Cost-Effectiveness of Transcatheter Mitral Valve Repair Versus Medical Therapy in Patients With Heart Failure and Secondary Mitral Regurgitation: Results From the COAPT Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed (...) to an existing collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Circulation Actions , 140 (23), 1881-1891 2019 Dec 3 Cost-Effectiveness of Transcatheter Mitral Valve Repair Versus Medical Therapy in Patients With Heart Failure and Secondary Mitral Regurgitation

2020 EvidenceUpdates

17. Efficacy and Safety of Mineralocorticoid Receptor Antagonists in Patients With Heart Failure and Chronic Kidney Disease

Efficacy and Safety of Mineralocorticoid Receptor Antagonists in Patients With Heart Failure and Chronic Kidney Disease Efficacy and Safety of Mineralocorticoid Receptor Antagonists in Patients With Heart Failure and Chronic Kidney Disease - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features are temporarily (...) : Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Review Am J Cardiol Actions 2019 Nov 19 [Online ahead of print] Efficacy and Safety of Mineralocorticoid Receptor Antagonists in Patients With Heart Failure and Chronic Kidney Disease , , , , , Affiliations Expand Affiliations 1 Department of Medicine, Warren Alpert School of Brown University

2020 EvidenceUpdates

18. End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV

End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV | JACC: Heart Failure Advertisement User menu Source Search for this keyword Search Source Search for this keyword Search JACC: Heart Failure DOI: 10.1016/j.jchf.2020.04.001 Letter to the Editor Just Accepted End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV Nianguo Dong , Jie Cai (...) , Ying Zhou , Junwei Liu and Fei Li Author + information DOI: Published By: Print ISSN: Online ISSN: Copyright & Usage: © 2020 Author Information This is a PDF-only article. The first page of the of this article appears above. Toolbox Thank you for your interest in spreading the word about JACC: Heart Failure NOTE: We request your email address only as a reference for the recipient. We do not save email addresses. Your Email * Your Name * Send To * Enter multiple addresses on separate lines

2020 American College of Cardiology

19. L-carnitine supplementation in the recovery of plasma L-carnitine in patients with heart failure submitted to coronary artery bypass grafting. Full Text available with Trip Pro

L-carnitine supplementation in the recovery of plasma L-carnitine in patients with heart failure submitted to coronary artery bypass grafting. Coronary artery bypass grafting reduces plasma L-carnitine and may impair the production of myocardial energy. L-carnitine supplementation may elevate plasma L-carnitine and increase cardiac mechanical efficiency. The objective of this study was to verify the recovery of preoperative plasma LC in patients with heart failure undergoing coronary artery (...) postoperative day, there was a reduction in plasma L-carnitine in groups A (17.4%) and B (14.4%). In the comparison between the groups, plasma L-carnitine was higher in group A than B in 10º (p = 0.024), 30º (p = 0.001), and 60º postoperative day (p = 0.008). Supplementation of L-carnitine at a daily oral dose of 50 mg / kg in patients with heart failure undergoing coronary artery bypass grafting may recover preoperative plasma L-carnitine within 10 days.

2019 Anais da Academia Brasileira de Ciencias Controlled trial quality: uncertain

20. Data-supported timely management in cooperation with a centre for telemedicine for patients with advanced cardiac failure - rapid report

-ventricular ejection fraction MCS Mental Health Composite Scale MLHFQ Minnesota Living with Heart Failure Questionnaire NYHA New York Heart Association OR odds ratio PCS Physical Composite Scale RCT randomized controlled trial SAE serious adverse event SF-36 Short Form (36) Health Survey SGB Sozialgesetzbuch (Social Code Book) TM telemedicine VAS visual analogue scale Extract of rapid report N19-01 Version 1.0 Telemonitoring in advanced cardiac failure 27 September 2019 Institute for Quality (...) of the heart to supply the organism with sufficient oxygen to ensure metabolism under both resting and exercise conditions [2]. It is a common disease in the older population [1] and is one of the most common causes of death in Germany [3]. Severity of cardiac failure is usually classified according to the New York Heart Association criteria (NYHA) [4]. However, the NYHA stage is not stable, i.e. it can change in one and the same person [4] and also relies heavily on the physician’s subjective assessment

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)