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Latest & greatest articles for hypothermia
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Plastic Bags for Prevention of Hypothermia in Preterm and Low Birth Weight Infants Hypothermia contributes to neonatal mortality and morbidity, especially in preterm and low birth weight infants in developing countries. Plastic bags covering the trunk and extremities of very low birth weight infants reduces hypothermia. This technique has not been studied in larger infants or in many resource-limited settings. The objective was to determine if placing preterm and low birth weight infants inside (...) infants (P < .001). Hyperthermia (>38.0°C) did not occur in any infant.Placement of preterm/low birth weight infants inside a plastic bag at birth compared with standard thermoregulation care reduced hypothermia without resulting in hyperthermia, and is a low-cost, low-technology tool for resource-limited settings.
Whole-Body Hypothermia for Term and Near-Term Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Controlled Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?
Hypothermia for neuroprotection in children after cardiopulmonary arrest. Cardiopulmonary arrest in paediatric patients often results in death or survival with severe brain injury. Therapeutic hypothermia, lowering of the core body temperature to 32°C to 34°C, may reduce injury to the brain in the period after the circulation has been restored. This therapy has been effective in neonates with hypoxic ischaemic encephalopathy and adults after witnessed ventricular fibrillation cardiopulmonary (...) arrest. The effect of therapeutic hypothermia after cardiopulmonary arrest in paediatric patients is unknown.To assess the clinical effectiveness of therapeutic hypothermia after paediatric cardiopulmonary arrest.We searched the Cochrane Anaesthesia Review Group Specialized Register; Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 11); Ovid MEDLINE (1966 to December 2011); Ovid EMBASE (1980 to December 2011); Ovid CINAHL (1982 to December 2011); Ovid BIOSIS
[Evidence overview of therapeutic hypothermia] Therapeutische hypothermie (TH): evidenzubersicht [Evidence overview of therapeutic hypothermia] Therapeutische hypothermie (TH): evidenzubersicht [Evidence overview of therapeutic hypothermia] Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Therapeutische hypothermie (TH): evidenzubersicht (...) . [Evidence overview of therapeutic hypothermia] Vienna: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBIHTA). Decision Support Document Nr. 63. 2012 Authors' conclusions The present overview of evidence shows that there is evidence only for the efficacy and safety of one (cardiac arrest) out of 11 reviewed indications of therapeutic hypothermia. From the large number of ongoing or recently finished trials it can be seen that therapeutic hypothermia is a dynamic field of research. Hence
Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review de Brito Poveda V, Martinez EZ, Galvao CM CRD summary This review concluded that, compared with forced-air warming, circulating water garments were more effective in maintaining the temperature of patients during surgery (...) ; carbon-fibre systems were as effective as forced air. The trials were generally small and of low quality and there were flaws in the search and review processes. The conclusions should be treated with caution. Authors' objectives To assess the effectiveness of different active cutaneous warming systems to prevent hypothermia during surgery. Searching MEDLINE, CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), and EMBASE were searched for articles from 2000 to August 2010. Search terms
Accidental hypothermia. 23150960 2012 11 27 2013 02 14 1533-4406 367 20 2012 Nov 15 The New England journal of medicine N. Engl. J. Med. Accidental hypothermia. 1930-8 10.1056/NEJMra1114208 Brown Douglas J A DJ Department of Emergency Medicine, University of British Columbia, Vancouver General Hospital, Vancouver, BC V5Z 1M9, Canada. email@example.com Brugger Hermann H Boyd Jeff J Paal Peter P eng Journal Article Review United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med (...) . 2013 Feb 14;368(7):681-2 23406043 N Engl J Med. 2013 Feb 14;368(7):681 23406042 N Engl J Med. 2013 Jan 24;368(4):394 N Engl J Med. 2013 Feb 14;368(7):682 23406041 Extracorporeal Circulation Fluid Therapy Humans Hypothermia diagnosis etiology therapy Resuscitation methods Rewarming methods Transportation of Patients 2012 11 16 6 0 2012 11 16 6 0 2012 12 10 6 0 ppublish 23150960 10.1056/NEJMra1114208
Therapeutic hypothermia and prevention of acute kidney injury: a meta-analysis of randomized controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Intravascular Cooling Devices to Induce Therapeutic Hypothermia: Clinical Effectiveness and Safety Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid (...) to Induce Therapeutic Hypothermia: Clinical Effectiveness and Safety DATE: 12 June 2012 RESEARCH QUESTIONS 1. What is the clinical effectiveness of intravascular cooling devices for the induction of therapeutic hypothermia following cardiovascular or cerebrovascular events? 2. What is the clinical evidence regarding the safety of intravascular cooling devices for the induction of therapeutic hypothermia following cardiovascular or cerebrovascular events? KEY MESSAGE Two randomized controlled trials
Childhood outcomes after hypothermia for neonatal encephalopathy. We previously reported early results of a randomized trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy showing a significant reduction in the rate of death or moderate or severe disability at 18 to 22 months of age. Long-term outcomes are now available.In the original trial, we assigned infants with moderate or severe encephalopathy to usual care (the control group) or whole-body cooling (...) to an esophageal temperature of 33.5°C for 72 hours, followed by slow rewarming (the hypothermia group). We evaluated cognitive, attention and executive, and visuospatial function; neurologic outcomes; and physical and psychosocial health among participants at 6 to 7 years of age. The primary outcome of the present analyses was death or an IQ score below 70.Of the 208 trial participants, primary outcome data were available for 190. Of the 97 children in the hypothermia group and the 93 children in the control
Systemic hypothermia to prevent radiocontrast nephropathy (from the COOL-RCN Randomized Trial) Radiocontrast nephropathy (RCN) develops in a substantial proportion of patients with chronic kidney disease (CKD) after invasive cardiology procedures and is strongly associated with subsequent mortality and adverse outcomes. We sought to determine whether systemic hypothermia is effective in preventing RCN in patients with CKD. Patients at risk for RCN (baseline estimated creatinine clearance 20 (...) to 50 ml/min) undergoing cardiac catheterization with iodinated contrast ≥50 ml were randomized 1:1 to hydration (control arm) versus hydration plus establishment of systemic hypothermia (33°C to 34°C) before first contrast injection and for 3 hours after the procedure. Serum creatinine levels at baseline, 24 hours, 48 hours, and 72 to 96 hours were measured at a central core laboratory. The primary efficacy end point was development of RCN, defined as an increase in serum creatinine by ≥25% from
Hypothermia for neuroprotection after cardiac arrest: systematic review and individual patient data meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?
[Therapeutic hypothermia in patients who underwent cardiac arrest resuscitation] Hipotermia terapeutica en pacientes resucitados de un paro cardiaco [Therapeutic hypothermia in patients who underwent cardiac arrest resuscitation] Hipotermia terapeutica en pacientes resucitados de un paro cardiaco [Therapeutic hypothermia in patients who underwent cardiac arrest resuscitation] Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Regueiro A, Alcaraz (...) A, Valanzasca P, Elorriaga N, Romano M, Rojas J Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Regueiro A, Alcaraz A, Valanzasca P, Elorriaga N, Romano M, Rojas J. Hipotermia terapeutica en pacientes resucitados de un paro cardiaco. [Therapeutic hypothermia
[Therapeutic hypothermia in patients with stroke or brain trauma] Hipotermia terapeutica en pacientes con accidente cerebrovascular o traumatismo cerebral [Therapeutic hypothermia in patients with stroke or brain trauma] Hipotermia terapeutica en pacientes con accidente cerebrovascular o traumatismo cerebral [Therapeutic hypothermia in patients with stroke or brain trauma] Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Regueiro A, Alcaraz (...) . [Therapeutic hypothermia in patients with stroke or brain trauma] Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No 230. 2011 Authors' objectives To assess the available evidence on the efficacy, safety and issues related with coverage of therapeutic hypothermia in patients with stroke or brain trauma. Authors' conclusions Based on the results of the analyzed studies, there is no evidence to support the use of therapeutic hypothermia in patients
Video-EEG monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia Therapeutic hypothermia (TH) is becoming standard of care in newborns with hypoxic-ischemic encephalopathy (HIE). The prognostic value of the EEG and the incidence of seizures during TH are uncertain.To describe evolution of EEG background and incidence of seizures during TH, and to identify EEG patterns predictive for MRI brain injury.A total of 41 newborns with HIE underwent TH. Continuous video-EEG (...) was performed during hypothermia and rewarming. EEG background and seizures were reported in a standardized manner. Newborns underwent MRI after rewarming. Sensitivity and specificity of EEG background for moderate to severe MRI brain injury was assessed at 6-hour intervals during TH and rewarming.EEG background improved in 49%, remained the same in 38%, and worsened in 13%. A normal EEG had a specificity of 100% upon initiation of monitoring and 93% at later time points. Burst suppression and extremely low
Very early hypothermia induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial The inconsistent effect of hypothermia treatment on severe brain injury in previous trials might be because hypothermia was induced too late after injury. We aimed to assess whether very early induction of hypothermia improves outcome in patients with severe brain injury.The National Acute Brain Injury Study: Hypothermia II (NABIS: H II (...) ) was a randomised, multicentre clinical trial of patients with severe brain injury who were enrolled within 2·5 h of injury at six sites in the USA and Canada. Patients with non-penetrating brain injury who were 16-45 years old and were not responsive to instructions were randomly assigned (1:1) by a random number generator to hypothermia or normothermia. Patients randomly assigned to hypothermia were cooled to 35°C until their trauma assessment was completed. Patients who had none of a second set of exclusion
Hypothermia for Neuroprotection After Cardiac Arrest Hypothermia for Neuroprotection After Cardiac Arrest – TheNNTTheNNT Mild Therapeutic Hypothermia for Neuroprotection Following Cardiopulmonary Resuscitation (CPR) 6 for mortality In summary, for patients treated with mild hypothermia after CPR: Benefits in NNT 84% saw no benefit 16% were helped by having a neurologically-intact survival 1 in 6 were helped (neurologically-intact life saved) Harms in NNT 0% were harmed None were harmed View (...) As: NNT % Source: Efficacy Endpoints: Neurologic recovery (best outcome while in hospital, as measured by cerebral performance categories), survival to hospital discharge Harm Endpoints: Bleeding, pneumonia, sepsis, pulmonary edema, cardiac dysrhythmias Narrative: After the return of spontaneous circulation following cardiac arrest, neurologic injury may occur in the process of reperfusion. Past investigations have suggested that the induction of hypothermia in initially comatose survivors can help
Therapeutic hypothermia following cardiac arrest (IPG386) Overview | Therapeutic hypothermia following cardiac arrest | Guidance | NICE Therapeutic hypothermia following cardiac arrest Interventional procedures guidance [IPG386] Published date: March 2011 Share Save Guidance The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on Therapeutic hypothermia following cardiac arrest. Description People
Inditherm patient warming mattress for the prevention of inadvertent hypothermia Inditherm patient warming mattress for the prevention of inadvertent hypothermia | Guidance | NICE Inditherm patient warming mattress for the prevention of inadvertent hypothermia Medical technologies guidance [MTG7] Published date: August 2011 Guidance In March 2018, NICE reviewed this guidance and recommended it should be withdrawn as it has been updated replaced by the NICE guideline on (NICE guideline CG65
Therapeutic hypothermia initiated in the pre-hospital setting: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.